Dee Ann Casteel, Ph. D.

Associate Professor of Chemistry



Department of Chemistry
Bucknell University

Lewisburg PA 17837

phone 717/524-3675

fax 717/524-1739

casteeel@bucknell.edu

Courses Taught

CH211 Organic Chemistry I
every fall semester
9:30am - 11:00am Tuesdays and Thursdays

CH212 Organic Chemistry II
every spring semester
9:30am - 11:00am Tuesdays and Thursdays

CH361 Mechanisms of Organic Reactions
fall semester 1995, 1996

CH329 Advanced Organic Synthesis
spring semester 1998, 1999

CH351 Chemistry Seminar
spring semester 1997


Research Interests

organic synthesis
hetero-Diels-Alder preparation of substituted dihydropyrans
preparation of organic peroxides
synthesis of analogs of artemisinin
antimalarial compounds
artemisinin analogs
bicyclic trioxanes
peroxides
synthesis
biological activity
natural products
peroxy
biologically active
medicinal chemistry
antimalarial, antitumor, antiviral


Publications

"The Chemistry of Natural Products" (book review)
Casteel, D. A.
Journal of the American Chemical Society 1995, 117, (24) in press [The Chemistry of Natural Products. Edited by R. H. Thomson (University of Aberdeen). Blackie Academic & Professional: London. 1993. x + 452 $149.95. ISBN 0-7514-0014-9].

"Prolongation of the Intravascular Retention of Hemoglobin Modified with a Long-Chain Fatty Acid Derivative"
Fowler, S. A.; Andracki, J.; Hurst, G.; Honkan, V. A.; Walder, J.; Casteel, D. A.
Biomaterials, Artificial Cells and Immobilization Biotechnology, 1994, 22, 27-42.

"Synthesis and Antimalarial Evaluation of 2,3,5-Trioxabicyclo[2.2.3]nonanes, Models for the Putative Pharmacophore of Artemisinin"
Casteel, D. A.; Peri, S. P.
Bioorganic and Medicinal Chemistry Letters 1993, 3, 1707-1710.

"Anomalous 'Lossen-Type' Rearrangement. Synthesis of Functionalized Imidazolinones"
Casteel, D. A.; Gephart, R. S.; Morgan, T.
Heterocycles 1993, 36 (3), 485-495.

"Synthesis and Antimalarial Evaluation of 2,3,5-Trioxabicyclo[2.2.2]octanes, Models for the Putative Pharmacophore of Qinghaosu (Artemisinin)"
Casteel, D. A.; Jung, K.-E.; Gerena, L.; Milhous, W.
Bioorganic and Medicinal Chemistry Letters 1992, 2, 623-626.

"Peroxy Natural Products"
Casteel, D. A.
Natural Product Reports 1992, 9, 289-312.

"Steric and Electronic Effects in the Arylphosphate to Arylphosphonate Rearrangement"
Casteel, D. A.*; Peri, S. P.
Synthesis 1991, 691-693.

"Improved Synthesis of Secondary Hydroperoxides"
Casteel, D. A.; Jung, K.-E.
Journal of the Chemical Society, Perkin Transactions I, 1991, 2597-2598.

"Isoquinoline Quinones. Preparation of Saframycin Intermediates and a Total Synthesis of Mimosamycin"
Parker, K. A.; Casteel, D. A.
Journal of Organic Chemistry 1988, 53, 2847-2850

. "Synthesis of Properties of Pyrrolo[3,4-d]imidazoles. A New Fluorescent Heterocyclic System"
Casteel, D. A.; Leonard, N. J.
Journal of Organic Chemistry 1985, 50, 2450-2456.

"Synthesis of Properties of Pyrrolo[3,4-d]imidazoles. A New Fluorescent Heterocyclic System"
Casteel, D. A.
Ph. D. Dissertation, University of Illinois at Urbana-Champaign, University Microfilms, 1985.