Nuclear magnetic resonance (NMR) is a technique for determining the shapes and structures of molecules and their interactions. NMR succeeds in discovering the structural characteristics of molecules by observing weak signals from nuclei containing a magnetic property termed ‘spin’.
Fall '14 Crew : (group alums)
Brian W. Williams and David Rovnyak, “A closed-form solution for the optimal time evolution of an exponentially decaying signal with thermal noise”, Concepts in Magnetic Resonance A 43(2): 54-56 (2014). Abstract.
Christopher L. Suiter, Sivakumar Paramasivam, Guangjin Hou, Shangjin Sun, David Rice, Jeffrey C. Hoch, David Rovnyak, Tatyana Polenova, “Sensitivity gains, linearity and spectral reproducibility in nonuniformly sampled multidimensional MAS NMR spectra of high dynamic range”, J. Biomol. NMR 59: 57-73, (2014).
Rovnyak, D., Sarcone, M.S., Jiang, Z.,"Sensitivity Enhancement for Maximally Resolved Two-Dimensional NMR Spectra by Nonuniform Sampling" Magnetic Resonance in Chemistry 49(8), 483-491 (2011). Online
Kennedy, P.E, Francis, N., Rovnyak, D., Kastner, M.E., "Redetermination of cis-diaquadiglycolatozinc(II)", Acta Crystallographica Section E: Structure Reports Online E64, 1635 (2008). Online
D. Rovnyak, Kennedy, P.E, "Application of shaped adiabatic pulses to MQMAS spectrsoscopy of Spin 3/2 nuclei", Journal of Magnetic Resonance, 196, 191-199 (2009). DOI
Christine M. Hebling, Laura E. Thompson, Kyle W. Eckenroad, Gregory A. Manley, Roderick A. Fry, Karl T. Mueller, Timothy G. Strein, David Rovnyak, "Sodium Cholate Aggregation and Chiral Recognition of the Probe Molecule (R,S) 1,1’-binaphthyl-2,2’ diylhydrogenphosphate (BNDHP) Observed by 1H and 31P NMR Spectroscopy", Langmuir, 24, 13866-13874 (2008). Abstract
D. Rovnyak,"Tutorial on analytic theory for cross polarization in solid state NMR", Concepts Magn. Reson. Part A, 32, 254-276 (2008).
D. Rovnyak, R. Stockland Jr., Eds,"Modern NMR Spectroscopy in Education", American Chemical Society Symposium Seres No. 969, Oxford University Press (2007). (on Amazon)
1. We perform fundamental studies with solid state zinc NMR spectroscopy and X-ray crystallography in collaboration with the Kastner lab. Zinc-67 is one of the most difficult of all NMR nuclei to study! See also (4).
2. We collaborate with the Strein lab to understand the chirally selective solvation of binaphthyl compounds by bile salt micelles. This project includes fundamental studies to gain deeper insight into micelle formation by bile salts.
3. We develop and disseminate laboratory and course experiences that effectively introduce undergraduate students to NMR. See our NMR Education Link for more info and dowloads.
4. We are investigating the use of alternative data sampling and processing to accelerate and enhance the acquisition of multi-dimensional NMR data.