Associate Professor
Department of Biology and Cell Biology/Biochemistry Program
Bucknell University
| Biology Department Cell Biology/ Biochemistry Program |
Contact Info Ken Field, Ph.D.203A Biology Building Bucknell University Lewisburg, PA 17837 570-577-3814 570-577-3537 Fax Research I am interested in the effects of farnesyltransferase inhibitors (FTIs) on the immune system in both normal and pathological conditions. I became interested in how this class of anti-cancer drugs affect the immune system while showing that these drugs can block certain immune system cancers in mice (Field et al.). My students have shown that FTIs can affect the immune regulatory proteins called cytokines that are produced by T cells in mice that are undergoing transplant rejection and that this can delay the rejection of a mismatched skin graft (Gaylo et al.). We are now trying to understand how FTI treatment affects this and other immune responses in mice in order to determine if these experimental drugs might be useful for treating transplant patients. More information about Prof. Field's research can be found here. Undergraduate Research Bucknell students interested in conducting research with Prof. Field should contact him by e-mail ( ) to arrange an appointment. Opportunities are available for summer research or for Biol 399 research. Most research projects span at least two semesters and the summer so interested students should become involved in their sophomore or junior year. Students are expected to complete Cell Biology (Biol 352) and Immunology (Biol 348) while enrolled in research. Teaching
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