Darwinian Selection

The central dogma of biology states that genes code for amino acids that are linked together to form proteins. Three nucleotides code for a single amino acid. Mutations can occur at any one of those three sites, but all sites and types of mutation do not produce the same result. A synonymous mutation does not change the resulting protein. A nonsynonymous mutation does change the protein, possibly affecting its function. If this change in function helps the organism adapt to its environment, positive selection has occurred. If this change decreases the fitness of the organism, it will likely be purged from the genome, and purifying selection has occurred

This semester I will be testing a data set consisting of 19 nculear genes from 64 placental mammals for signs of selection. This project will examine the genes for molecular evolution. Check out my research proposal for more details. This is just one of the many things going on in Prof. Jordan's lab right now.

Check out the site later as I get going on my research ...

 

 

Todd...