Research Interests; Structure-Function Studies of Signaling Proteins for Pharmaceutical and Biotechnology Applications.

X-ray structure of an engineered PI-PLC enzyme solved by my group.  The active site histidines are shown as sticks and the active site Ca⁺² atom as a yellow sphere.  Details can be found at the Protein Data Bank (ID Code: 1T6M) 

Research Projects

(follow each link for further information)

 

· Enzyme Specificity and Single Molecule Detection of Catalytic Events

 

· X-ray structure determination of Novel PI-PLC Signaling Enzymes

 

· Investigating Transitional Mechanisms in Apoptosis Signaling using Computational and Bioinformatics Approaches

 

 

Teaching Interests

(follow each link for further information)

 

· Biochemistry Lecture and Biochemistry Lab

· Inorganic Chemistry

· Special Topics: X-ray Structure Determination of Proteins and Bioinformatics.

 

 

Bucknell University

 

Chemistry Department

 

Biochemistry Program

 

Group Members

 

Publications

 

Research Funding

 

Awards

Department of Chemistry

Cell Biology/Biochemistry Program

209 Rooke Chemistry Bldg

Phone: 570-577-1042

FAX: 570-577-1739

tom.selby@bucknell.edu

Mailing address:

 

Department of Chemistry
209 Rooke Chemistry Building
Bucknell University
Lewisburg, PA 17837

 

 

Phone: 570-577-1042

FAX: 570-577-1739

tom.selby@bucknell.edu