Peer-Reviewed Publications

 

 

 

17) “Characterization of a Randomized FRET Library for Protease Specificity Determination”

Jonathan F. Fretwell, Shams M. K. Ismail, and Thomas L. Selby, Molecular BioSystems, In Press Manuscript reference: B709290C (2008)

 

16) “Computational Active Site Analysis of Molecular Pathways to Improve Functional Classification of Enzymes” Ozyurt, A. and Selby, T.L. PROTEINS: Structure, Function, and Bioinformatics, Jan 23;72(1):184-196 (2008) 

 

15) “X-ray structure of the R69D phosphatidylinositol-specific phospholipase C enzyme: Insight into the role of calcium and surrounding amino acids in active site geometry and catalysis.”  D Apiyo, L Zhao, MD Tsai, TL Selby, Biochemistry 44 (30): 9980-9989 August 2 (2005)

 

14) “Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 angstrom resolution.” Schwarzenbacher R, von Delft F, Canaves JM, Brinen LS, Dai XP, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, Lesley SA, McMullan D, McPhillips TM, Miller MA, Miller MD, Morse A, Moy K, Ouyang J, Page R, Robb A, Rodrigues K, Selby TL, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, Wang XH, West B, Wolf G, Hodgson KO, Wooley J, Wilson IA Proteins-Structure Function and Genetics 54 (1): 174-177 JAN 1 (2004)

 

13) “Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution.” Heine A, Canaves JM, von Delft F, Brinen LS, Dai XP, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, Lesley SA, McMullan D, McPhillips TM, Miller MA, Morse A, Moy K, Ouyang J, Page R, Robb A, Rodrigues K, Schwarzenbacher R, Selby TL, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, Wang XH, West B, Wolf G, Hodgson KO, Wooley J, Wilson IA. Proteins-Structure Function and Bioinformatics 56 (2): 387-391 AUG 1 (2004)

 

12) “Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 angstrom resolution.”  Schwarzenbacher R, Canaves JM, Brinen LS, Dai XP, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, Lesley SA, McMullan D, McPhillips TM, Miller MA, Miller MD, Morse A, Moy K, Ouyang J, Robb A, Rodrigues K, Selby TL, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, Wang XH, West B, Wolf G, Hodgson KO, Wooley J, Wilson IA.  Proteins-Structure Function and Genetics 53 (1): 142-145 OCT 1 (2003)

 

11) “Crystal structure of a zinc-containing glycerol dehydrogenase (TM0423) from Thermotoga maritima at 1.5 angstrom resolution”, Brinen LS, Canaves JM, Dai XP, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, Lesley SA, McMullan D, McPhillips TM, Miller MA, Miller MD, Morse A, Moy K, Jie OY, Robb A, Rodrigues K, Selby TL, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, Wang XH, West B, Wolf G, Taylor SS, Hodgson KO, Wooley J, Wilson IA, Proteins-Structure Function and Genetics 50 (2): 371-374 FEB 1 (2003)

 

10) "Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline"  S.A. Lesley, P. Kuhn, A. Godzik, A.M. Deacon, I. Mathews, A. Kreusch, G. Spraggon, H.E. Klock, D. McMullan, T. Shin, J. Vincent, A. Robb, L.S. Brinen, M.D. Miller, T.M. McPhillips, M.A. Miller, D. Scheibe, J.M. Canaves, C. Guda, L. Jaroszewski, T.L. Selby, M.A. Elsliger, J. Wooley, S.S. Taylor, K.O. Hodgson, I.A. Wilson, P.G. Schultz, R.C. Stevens  Proc. Natl. Acad. Sci. USA, 99, 11664-11669 (2002).

 

9) "Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 A resolution"  P. Kuhn, S.A. Lesley, I.I. Mathews, J.M. Canaves, L.S. Brinen, X. Dai, A.M. Deacon, M.A. Elsliger, S. Eshaghi, R. Floyd, A. Godzik, C. Grittini, S.K. Grzechnik, C. Guda, K.O. Hodgson, L. Jaroszewski, C. Karlak, H.E. Klock, E. Koesema, J.M. Kovarik, A.T. Kreusch, D. McMullan, T.M. McPhillips, M.A. Miller, M. Miller, A. Morse, K. Moy, J. Ouyang, A. Robb, K. Rodrigues, T.L. Selby, G. Spraggon, R.C. Stevens, S.S. Taylor, H. van den Bedem, J. Velasquez, J. Vincent, X. Wang, B. West, G. Wolf, J. Wooley, I.A. Wilson Proteins: Structure, Function and Genetics, 49, 142-145 (2002).

 

8) “Tumor Suppressor INK4:  Solution Structure of p15INK4B, Refined Solution Structure of p16INK4A, and Structural Comparison of INK4 Proteins.”  Thomas L. Selby, Chunhua Yuan, Junan Li, In-Ja Byeon, and Ming-Daw Tsai. Protein Science. Jun;9(6):1120-8 (2000)

7) “Tumor Suppressor INK4:  Quantitative Structure-Function Analyses of p18INK4C as an Inhibitor of Cyclin-Dependent Kinase 4.” Junan Li, Ming Jye Poi, Dongyan Qin, Thomas L. Selby, In-Ja Byeon, and Ming-Daw Tsai,  Biochemistry. Feb 1;39(4):649-57 (2000)

 

6) “Tumor Suppressor INK4:  Comparisons of Conformational Properties between p15INK4B, p16INK4A, and p18INK4C.”  Chunhua Yuan, Junan Li, Thomas L. Selby, In-Ja Byeon, and Ming-Daw Tsai, J Mol Bio., 294, 201-211 (1999)

 

5) “Tumor Suppressor INK4:  3. Determination of the Solution Structure of p18INK4C and Demonstration of the Functional Significance of Loops in p18INK4C and p16INK4A.” Junan Li, In-Ja L. Byeon, Karen Ericson, Ming Jye Poi, Paul O’Maille, Thomas Selby, and Ming-Daw Tsai, Biochemistry 38, 2930-2940 (1999).

 

4) "Tumor Suppressor p16INK4A:  2. Determination of Solution Structure and Analyses of Its Interaction with Cyclin-Dependent Kinase 4".  In-Ja L. Byeon, Junan Li, Karen Ericson, Thomas L. Selby, Anton Tevelev, Hee-Jung Kim, Paul O'Maille, and Ming-Daw Tsai, Molecular Cell 1, 421-431 (1998).

 

3) “Tumor Suppressor INK4:  3. Determination of the Solution Structure of p18INK4C and Demonstration of the Functional Significance of Loops in p18INK4C and p16INK4A.” Junan Li, In-Ja L. Byeon, Karen Ericson, Ming Jye Poi, Paul O’Maille, Thomas Selby, and Ming-Daw Tsai, Biochemistry 38, 2930-2940 (1999).

 

2) “Tumor suppressor p16-INK4A: Structural characterization of wild-type and mutant proteins by NMR and circular dichroism.”  Tevelev A, Byeon IJ, Selby T, Ericson K, Kim HJ, Kraynov V, Tsai MD.  Biochemistry, Jul 23;35(29):9475-9487 (1996)

 

1) “Dissociation Characteristics of [M + X]+ Ions (X = H, Li, Na, K) from Linear and Cyclic Polyglycols.” Selby, T.L., Wesdemiotis, C., Lattimer, R.P.  J Am Soc Mass Spectrom, , Volume 5, 1081-1092 (1994)

 

 

  

 

Book Chapters

 

3) "Robotics for Automated Crystal Formation and Analysis"   M. Weselak, M.G. Patch, T.L. Selby, G. Knebel, R.C. Stevens, Macromolecular Crystallography, Part C. Methods in Enzymology 368: 45-76 (2003).

 

2) "Bioinformatics and high-throughput protein production for structural genomics"  T.L. Selby, R.C. Stevens Gene Cloning and Expression Technologies, Eaton Publishing (2002).

 

1) “Structure-Function Relationship of the INK4 Family of Tumor Suppressors”.  Junan Li, In-Jia L. Byeon, Ming Jye Poi, Karen Ericson, Thomas Selby, Paul O’Maille, Dongyan Qin, and Ming-Daw Tsai, in DNA Alterations in Cancer: Genetic and Epigenetic Changes, Melanie Ehrlich, Ed., BioTechniques Books, Eaton Publishing (1999)

 

 

  

Published Meeting Abstract(s)

 

1) "Inside-Out" methods to determine enzyme active site structures for drug design Selby TL, FASEB JOURNAL 19 (4): A303-A304 Part 1 Suppl. S, MAR 4 (2005)

 

 

 

Undergraduate Research Journal

 

1) Barbara C. Mascareno-Shaw and Thomas L. Selby, “Computational Analysis of Broad Complex Zinc-Finger Transcription Factors” UCF Undergraduate Research Journal.